Belma implants consist of a polymer reservoir surrounded by a hormone diffusion-controlling membrane. They are designed to release daily doses of a hormone to produce physiological or pharmacological plasma concentrations in mice and rats.
Table 1 : Plasma concentrations, normal values
| Rat | Mouse | |
| E2 (pg/ml) | 2,4 – 145,4 | 2,4 – 145,4 |
| P4 (ng/ml) | 1,2 – 18,4 | 1,2 – 18,4 |
| T (ng/ml) | 0,66 – 5,4 | 1,7 – 14,4 |
Table 2 : Concentrations plasmatiques, valeurs mesurées avec les implants Belma
| Rat | Mouse | |
| Belma E2 (pg/ml) | 52 - 108 | 41,2 - 105,6 |
| Belma E2L (pg/ml) | 35,2 - 72,0 | |
| Belma P4 (ng/ml) | 5,3 – 11,2 | 3,0 - 5,9 |
| Belma T (ng/ml) | 0,9 - 3,7 | 2,9 - 7,5 |
Our offer :
| Animal | Reference | Release time |
| Mouse | P4-M/30 | 30 days |
| P4-M/60 | 60 days | |
| P4-M/90 | 90 days | |
| Rat | P4-R/30 | 30 jours |
| P4-R/60 | 60 jours | |
| P4-R/90 | 90 jours |
